Menu:

 

 

Contact:

 

Methodology


Single Particle Analysis

The 2D/3D alignment by classification workflow avoiding reference bias:

Single-particle cryo-EM using alignment by classification (ABC): the structure of Lumbricus terrestris haemoglobin
IUCrJ 4 (2017) 678-694.

4D Image Analysis

Working on data-sets containing mixed populations of particles using programs looping over stacks of 3-D volumes:

Four-Dimensional Cryo Electron Microscopy at Quasi Atomic Resolution: IMAGIC 4D
International Tables for Crystallography Volume F: Crystallography of biological macromolecules (Second Edition) Editors: E. Arnold, D. M. Himmel and M. G. Rossmann. International Tables for Crystallography Volume F. ISBN: 978-0-470-66078-2 (2011) 624-628.

Multivariate Statistical Analysis

Multivariate Statistical Analysis of Large Datasets: Single Particle Electron Microscopy
Open Journal of Statistics 6 (2016) 701-739.

Angular Reconstitution

Links to: www.ecmjournal.org

Angular Reconstitution in Three-dimensional Elecron Microscopy: Historical and Theoretical Aspects
Scanning Microscopy 11 (1997) 195-210.

Angular Reconstitution in Three-dimensional Elecron Microscopy: Practical and Technical Aspects
Scanning Microscopy 11 (1997) 179-193.

Fourier Ring Correlation

The first "Fourier Ring Correlation" paper:
Arthropod Hemocyanin Structures studied by Image Analysis
Life Chemistry Reports, Suppl. 1 (1982) 69-73.

Point-Group Symmetry

Pointgroup Symmetry of oligometric macromolecules

Camera Correction

A posteriori correction of camera characteristics from large image data sets
Scientific Reports 510317; doi: 10.1038/srep10317 (2015)

Phase Contrast (Electron) Microscopy

Principles of Phase Contrast (Electron) Microscopy


In Memoriam

Jean-Pierre Brètaudiere and the early days of MSA in EM


Links to references, Hands-ons:

Single Particles - Publications
Single Particles - Manuals / Hands-On